Discover how PIM2-mediated phosphorylation of PFKFB4 drives endometriosis progression through metabolic reprogramming and anaerobic glycolysis.
Discover how Glutathione Peroxidase-1 acts as a master regulator of protein metabolism, reshaping our understanding of antioxidants and body composition.
Discover how bioinformatic pipelines identify change-of-function mutations that reprogram cancer cell metabolism, opening new avenues for targeted therapies.
Discover how TRIM29 reprograms glucose metabolism in colorectal cancer through pyruvate kinase manipulation and the Warburg effect.
Discover how the GLS1-c-Myc positive feedback loop drives cancer progression and new therapeutic strategies to break this vicious cycle.